姓名 |
赵兴洪 |
政治面貌 |
中共党员 |
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导师类型 |
硕士生导师 |
办公地点 |
6教308 |
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职称/职务 |
副教授 |
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电子邮箱 |
xinghong.zhao@sicau.edu.cn |
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研究方向 |
细菌耐药性控制:肽类抗生素及其精准递送系统 |
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学术、技术组织任职/头衔 |
四川省特聘专家、四川省“天府峨眉计划”青年科技人才、著名传染病学国际学术期刊ACS Infectious Diseases副主编。 |
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教育背景及工作经历 |
2023/04至今best365网页版登录官方网站副教授 2021/08-2023/03 best365网页版登录官方网站特聘副教授 2020/06–2021/08荷兰格罗宁根大学微生物与生化药学博士后 2017/08–2020/06荷兰格罗宁根大学微生物与生化药学博士 |
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教学课程 |
生物技术制药、仪器分析(药) |
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人才培养情况 |
指导在读硕士生5名、本科生8名 |
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科研项目 (近五年) |
1、四川省自然科学基金面上项目,2024.11-2026.10,在研,主持 2、天府英才工程专项,2023.04-2026.03,在研,主持 3、四川省国际科技创新合作面上项目,202201-202312,结题,主持 4、best365网页版登录官方网站引进人才科研启动项目,202108-202607,在研,主持 |
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主要论著、 代表性论文 |
现已发表SCI收录论文30余篇,被Chemical reviews、Trends in Biotechnology和Nature Communications等国际著名期刊引用1400余次,H指数22。近五年以第一作者或通讯作者(含共同)在Nature Communications(2024, IF=16.6)、Advanced Science(2024, IF=14.3)、Cell Chemical Biology(2020, IF=9.039)、Advanced Materials(2024, IF=27.4)、Advanced Healthcare Materials(2024, IF=10)、International Journal of Biological Macromolecules(2024, IF=8.2)和Journal of Controlled Release(2024, IF=10.8)等专业领域权威期刊发表SCI收录论文20余篇,系统的解决了细菌耐药性控制中的多项难题。代表性论文如下: [1]Xinghong Zhao#,*, Xinyi Zhong#, Shinong Yang#, Jiarong Deng, Kai Deng, Zhengqun Huang, Yuanfeng Li, Zhongqiong Yin*, Yong Liu*, Jakob H. Viel, and Hongping Wan*. "Guiding antibiotics towards their target using bacteriophage proteins."NatureCommunications,2024, 15: 5287.(IF = 16.6,第一作者兼通讯作者) [2] Hongping Wan#,*, Xinyi Zhong#, Shinong Yang#, Jiarong Deng#, Xu Song, Yong Liu*, Yuanfeng Li*, Zhongqiong Yin,Xinghong Zhao*. "Enhancing the Therapeutic Potential of Peptide Antibiotics Using Bacteriophage Mimicry Strategies. "Advanced Science, 2024, 2411753. (IF = 14.3,最后一位通讯作者) [3]Xinghong Zhao, Zhibo Li, and Oscar P. Kuipers*. "Mimicry of a Non-ribosomally Produced Antimicrobial, Brevicidine, by Ribosomal Synthesis and Post-translational Modification."Cell Chemical Biology,2020, 27(10): 1262-1271.(IF = 9.039,第一作者) [4] Xiaowen Hu, Dongdong Li, Huaping Li, Yinzi Piao*, Hongping Wan, Tieli Zhou, Mahdi Karimi,Xinghong Zhao*, Yuanfeng Li*, Linqi Shi, Yong Liu*. "Reaction-Induced Self-Assembly of Polymyxin Mitigates Cytotoxicity and Reverses Drug Resistance."Advanced Materials,2024, 2406156. (IF = 27.4,共同通讯作者) [5] Kai Deng#, Zhengqun Huang#, Bo Jing, Lin Zhu, Yumei Feng, Qin Jiang, Zhiwen Xu, Hongping Wan*, andXinghong Zhao*. "Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization."International Journal of Biological Macromolecules,2024, 133008.(IF = 8.2,最后一位通讯作者) [6] Yumeng Wang#,Xinghong Zhao#, Xingjian Zhou#, Juqin Dai, Xiaowen Hu, Yinzi Piao, Guangyue Zu, Jian Xiao*, Keqing Shi*, Yong Liu*, Yuanfeng Li*, and Linqi Shi. "A supramolecular hydrogel dressing with antibacterial, immunoregulation, and pro-regeneration ability for biofilm-associated wound healing."Journal of Controlled Release,2024, 368:740-755.(IF = 10.8,共同第一作者) [7] Hongping Wan#,*, Kai Deng#, Zhengqun Huang#, Yunhan Yang, Bo Jing, Yumei Feng, Yuanfeng Li, Yong Liu, Mingqin Liu, andXinghong Zhao*. "Pathogen-mimicking Nanoparticles Based on Rigid Nanomaterials as an Efficient Subunit Vaccine Delivery System for Intranasal Iimmunization."Advanced Healthcare Materials,2024, 2401120.(IF = 10,最后一位通讯作者) [8]Xinghong Zhao#,*, Xinyi Zhong#, Shinong Yang#, Kai Deng, Lu Liu, Xu Song, Yuanfeng Zou, Lixia Li, Xun Zhou, Renyong Jia, Juchun Lin, Huaqiao Tang, Gang Ye, Jianqing Yang, Shan Zhao, Yifei Lang, Hongping Wan*, Zhongqiong Yin*, and Oscar P. Kuipers. "Elucidating the Mechanism of Action of the Gram-Negative-Pathogen-Selective Cyclic Antimicrobial Lipopeptide Brevicidine."Antimicrobial Agents and Chemotherapy,2023:e00010-23.(IF = 5.938,第一作者兼通讯作者) [9]Xinghong Zhao, Zhongqiong Yin, Eefjan Breukink, Gert N. Moll, and Oscar P. Kuipers*. "An engineered double lipid II binding motifs-containing lantibiotic displays potent and selective antimicrobial activity against Enterococcus faecium."Antimicrobial Agents and Chemotherapy,2020, 64(6): e02050-19.(IF = 5.938,第一作者) [10] Yongcheng He#, Jiarong Deng#, Xinyi Zhong#, Shujun Dai, Xu Song, Yuanfeng Zou, Gang Ye, Xun Zhou, Zhongqiong Yin, Hongping Wan*,Xinghong Zhao*. "Engineered Hybrid Lantibiotic that Selectively Combats Infections Caused by Staphylococcus aureus."ACS Infectious Diseases,2024.(IF = 4,最后一位通讯作者) |